Hubris, Heat, and a Humbling Dose of NAD+

 Welcome back to another episode of "Please Just Listen to Your Doctor," broadcasting live from the IV chairs at CoreRestore Infusions.

Today’s cautionary tale features a couple visiting us from overseas. They found us through word-of-mouth and were eager to sample our IV offerings.

Let's set the stage:
The wife was sensible, grounded, and delightful.
The husband? A towering picture of youth and strength who looked like he probably bench-presses small vehicles for fun.

They wanted the holy grail of IV therapy: NAD+.

The "Spicy Drip" Warning Label

Whenever a patient asks for NAD+, I get excited, but I also have to deliver My Speech™. I walked them through the amazing benefits, but I also made it crystal clear that NAD+ is a bit of a diva.

If you pump it in too fast, your body throws a spectacular tantrum. I explicitly warned them about the risks of a rapid infusion:

• Intense, sudden body heat

• A racing heart

• Flushing (turning into a human tomato)

• Mild disorientation and chest tightness

Because of this, NAD+ requires constant supervision and a nice, slow, leisurely drip rate.

The wife nodded, perfectly happy to chill out and take hers over a sensible two hours.

The husband? He literally scoffed. He puffed out his chest, boldly proclaimed that he is "strong" and nothing would happen to him, and insisted we wrap his session up in one hour flat.

We got them hooked up. For the first ten minutes, I played it safe and ran his drip at a snail's pace.

Nothing happened. He was totally fine.

The wife was happy to let us gradually increase her rate. The husband, however, took this initial ten minutes of peace as scientific proof of his invincible biology. He looked at me and insisted we go "full throttle."

Against my better judgment, but knowing a bruised ego was the only cure for this level of hubris, I bumped up the rate.

The Three-Minute Meltdown

It took exactly three to four minutes for his tough-guy facade to completely dissolve.

Ta-da! Suddenly, his face flushed a brilliant, glowing shade of crimson. A layer of panic-sweat broke out across his forehead. He gripped the armrests like he was on a rollercoaster, experiencing that classic mild chest tightness I had warned him about.

 

When he finally spoke, his booming, confident voice had vanished. It was replaced by a fragile, squeaky little whisper. Very sheepishly, he looked at me and begged me to please turn the dial down. About sixty seconds later, he asked me to just stop it completely so he could remember how to breathe.

I kid you not—his wife looked over from her perfectly comfortable, slow-dripping chair and absolutely lost it. She was cackling at him. It was poetic justice in its purest form.

After a brief time-out to let his heart rate (and his pride) recover, we started him back up on the slow setting. They finished their treatments together over the next hour and a half, and he solemnly promised that the next time he sits in my clinic, he will actually listen to the expert.

The Moral of the Story: NAD+ is an absolute powerhouse of a drip. It offers incredible health benefits, including anti-inflammatory effects, pain mediation, cellular repair and regeneration, and anti-aging properties.

But you have to respect the drip! It must be administered carefully and monitored constantly. If you want the safest possible infusions—overseen by qualified healthcare professionals who will absolutely say "I told you so" when you ignore their advice—come see us at CoreRestore Infusions.

Ecstasy, Agony, and an IV Drip

First things first: we are back to writing about bizarre clinical encounters because it’s time to return to my roots. Oddly enough, these crazy cases always seem to find me around August—which is highly appropriate, considering I started this very blog in an August past.

Anyway, let’s set the scene. 

Enter: a couple presenting with a truly peculiar cocktail of complaints. Their symptom list read like a medical mystery:

• Mild confusion & dizziness

• Spiraling anxiety

• Total lack of sleep

• General listlessness

• A dash of hypotension

The severity of these symptoms was bouncing back and forth between the two of them like a ping-pong ball. After a little gentle prodding, the confession finally spilled out.

The culprit? MDMA.

And not just a one-off. Oh no, they went for the hat-trick: three consecutive days at a music festival.

The Law of Diminishing Returns

If you know anything about how these things work, you can guess how the weekend went:

• Day 1 went exactly as advertised: a true trip where every sense was heightened, and the vibes were immaculate.

• Day 2 arrived with high expectations, but delivered a noticeably watered-down effect.

• Day 3 was a total dud. The magic was officially gone, replaced by a lingering feeling of absolutely nothing happening.

Then came the ultimate mood-killer: a long-haul flight back to the motherland.

That’s when the serotonin debt came calling, and everything crashed down at once. Panic unpacked its bags and settled in, sleep completely evaporated, worry lines deepened, and their nervous systems started flashing red warning lights. After toughing it out for two agonizing days—praying it would just magically fade—they finally walked through the doors of CoreRestore Infusions searching for salvation.

The Fix & The Plot Twist

We hooked them up with one of our signature hangover flushes—a bespoke cocktail of vitamins, minerals, and chelating agents designed to hit the reset button.

Initially, the husband seemed to be weathering the storm much better than his better half. Both tolerated the IV drip beautifully and went home feeling relieved, crossing their fingers that the worst was behind them.

Plot twist!

By the next morning, the wife had bounced back completely. The husband, however, decided that post-MDMA-comedown-recovery was the perfect time to aggressively exert himself playing a sport. Spoiler alert: it was not. He felt significantly worse, earning himself a ticket back to our clinic for Round Two.

While he was hooked up to his second drip, his wife chilled out beside him, looking 100% back to normal. Fortunately, by the time his IV bag was empty, he was finally out of the woods. They managed to catch their flight back home just in time for a massive, unmissable event. All's well that ends well!

The Moral of the Story: MDMA can't make everyone happy—especially if you try to stretch it over a three-day weekend. Stay away from recreational drugs if you can help it. (But if you do crash, you know who to call).

Retatrutide - A New Option for Metabolic Health

 

Retatrutide at CoreRestore

A New Option for Metabolic Health

What is Retatrutide?

• A new therapy being studied for weight management and metabolic health.
• Works on three hormone pathways (GLP‑1, GIP, and glucagon) to help control appetite, energy use, and blood sugar.
• Early studies show promising results for patients with obesity and related conditions.

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Why We Offer It

At CoreRestore, we bring safe, science‑backed innovations to patients who are open to trying new therapies. Retatrutide is offered under strict medical supervision to ensure safety and effectiveness.

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How It’s Given

• Once‑a‑week injection under the skin (subcutaneous), similar to using an insulin syringe.
• The dose is tailored to each patient’s weight‑loss goals and side‑effect profile.
• Gradual dose increase to reduce side effects.
• Regular monitoring of weight, blood sugar, and overall wellbeing.

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Safety First

• Careful patient screening before starting.
• Informed consent and clear education about benefits and risks.
• Follow‑up visits to track progress and adjust therapy if needed.

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What You May Experience

Potential Benefits

• Reduced appetite and improved satiety.
• Support for weight loss.
• Better blood sugar control.

Possible Side Effects

• Nausea, diarrhea, or constipation.
• Rare risks like pancreatitis or gallbladder issues (discussed upfront).
• Therapy paused or adjusted if side effects occur.

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Our Promise

Your safety and empowerment come first. Retatrutide is offered only to patients who understand its investigational nature and are comfortable with close monitoring. At CoreRestore, innovation is always paired with responsibility.

Contact us on:

Mobile: +91 8291347712
Landline: 02246023135
Instagram: @CoreRestoreinfusions
Email: corerestoreinfusions@gmail.com

🧬 From Aches and Pains to Proactive Power: Is Your Future Health Written in Your Genes?

🚗 The Check-Engine Approach to Health—Now Outdated

Remember two decades ago? When health advice sounded like a broken record?

“Get your annual check-up!”
“Preventive care is key!”

They weren’t wrong. Back then, detecting health issues early—like catching a rogue mole or blood pressure on the rise—was revolutionary. But if we’re being honest, it felt a lot like getting your car checked after the “check engine” light flicked on. Useful? Yes. But proactive? Not quite.

⚙️ 2025: The Year We Upgrade Our Health Game

Fast forward to now, and we’re rewriting the rulebook.

We're not just reacting to illness—we're outsmarting it. What if your body came with a built-in instruction manual? With advances in genetic testing and predictive health, it basically does. And trust us—it’s way more useful than any car manual you’ve ever owned.

Imagine knowing in advance where your health might go off-road. Not waiting for symptoms, but steering clear of them entirely.

🔮 Science Fiction? More Like Science Fact.

Think of genetic testing as your personal health crystal ball—but instead of vague predictions, you get:

• Personalized insights based on your DNA
• Early detection of risk factors
• Tailored lifestyle strategies
• Preemptive therapeutic interventions

We’re trading “detect and treat” for “predict and prevent.”

🧠 You, But Optimized

This isn’t about fear—it’s about freedom. Knowing your genetic risk doesn’t trap you; it empowers you. We can now adjust your nutrition, lifestyle, and medical care before an issue even begins.

No more one-size-fits-all advice. This is medicine fitted just for you

 🧪 Powered by Science. Driven by Passion.

At CoreRestore Infusions, under the guidance of Dr. Dheeraj Mulchandani, we’re on a mission:
To help you take control of your health story before it even begins.

Whether it’s:

• Mapping your genetic risks
• Crafting custom nutrient therapies
• Starting IV infusions tailored to your biology

We’re here to help you thrive—not just survive.

🌟 Your Future is Waiting

So why wait for the “surprise party” no one actually wants?
Step into the future of wellness with CoreRestore Infusions. Let’s make your health story not just good, but genetically brilliant.

📅 Book your consultation today with Dr. Dheeraj Mulchandani

Endoscopy after 40

Understanding the Silent Threat

Our bodies are complex machines. Sometimes, parts of this machine can develop problems without showing any early warning signs. This is especially true for your digestive system.

One such silent problem is cancer of the gut. While it might sound scary, the good news is that we can often find it early which makes it much easier to treat. This is where a screening endoscopy comes in.

The Indian Context

In India, unfortunately, many people are diagnosed with gut-related cancers at advanced stages. This often makes treatment difficult and reduces the chances of a full recovery. To change this, it's crucial to adopt preventive measures.

The Importance of Screening

A screening endoscopy is a simple procedure where a thin, flexible tube with a camera is gently inserted into your digestive tract. This allows us to examine the lining of your food pipe, stomach, and intestines for any abnormalities.

• Early Detection: We can often spot tiny, precancerous changes or even early-stage cancers that cause no symptoms. This gives us a chance to treat them before they become a bigger problem.
• Prevention: Removing precancerous growths can prevent cancer from developing altogether.
• Peace of Mind: Knowing your digestive system is healthy can significantly reduce worry and anxiety.
• Incidental findings: We can pick up non-cancerous ailments which could be causing you problems and treat them effectively 

When to Consider a Screening Endoscopy

While general recommendations suggest starting screening at 40, it’s essential to discuss your personal risk factors with your doctor. If you have a family history of gut-related cancers or other risk factors, you might need to start earlier.

Remember, prevention is always better than cure. A simple endoscopy can save your life. Don’t delay this important step in taking care of your health.

The reason for writing this at this time:

I came across a rare case of the Melkersson-Rosenthal Syndrome. 

That’s patient incidentally came for his endoscopy to check for Crohn’s disease.

The symptoms of Melkersson-Rosenthal Syndrome (MRS) present as a triad of:

1. persistent or recurrent upper lip oedema (oedema is a build-up of body fluid), 

2. relapsing facial paralysis and 

3. a fissure tongue. 

MRS is commonly associated with the more well known Crohn’s disease, a form of inflammatory bowel disease, diagnosed with a colonoscopy on routine investigations.

If you or your loved ones are diagnosed with Crohn’s, make sure to keep a look out for the triad of symptoms and ask your doctor about if any present themselves. 

A little extra caution goes a long way!

Preventing Cancer from HPV - For Girls and Boys both!

  

 Short answer -  Yes!

Most cervical cancers are associated with human papillomavirus (HPV).  It can spread through sex and from some types of skin-to skin-contact. Gardasil 9 is an HPV vaccine approved by the GOI and can be used for both girls and boys. This vaccine can prevent most cases of cervical cancer if the vaccine is given before girls or women are exposed to the virus. This vaccine can also prevent vaginal and vulvar cancer. In addition, the vaccine can prevent genital warts, anal cancers, and mouth, throat, head and neck cancers in women and men.

 

When exactly should the HPV vaccine be offered?

The recommendation is for HPV vaccine to be given to girls and boys between ages 11 and 12. It can be given as early as age 9. It's ideal for girls and boys to receive the vaccine before they have sexual contact and are exposed to HPV. The response to the vaccine is better at younger ages than it is at older ages.

The CDC recommends that all 11- and 12-year-olds receive two doses of HPV vaccine at least six months apart. Younger adolescents ages 9 and 10 and teens ages 13 and 14 also can receive vaccination on the two-dose schedule. Research has shown that the two-dose schedule is effective for children under 15.

Teens and young adults who begin the vaccine series later, at ages 15 through 26, should receive three doses of the vaccine.

 

Does the HPV vaccine offer benefits if you're already sexually active?

Yes. Even if you already have one strain of HPV, you could still benefit from the vaccine because it can protect you from other strains that you don't yet have. However, none of the vaccines can treat an existing HPV infection. The vaccines protect you only from specific strains of HPV you haven't been exposed to already.

 

Does the HPV vaccine carry any health risks or side effects?

The HPV vaccine has been found to be safe in many studies.

Overall, the effects are usually mild. The most common side effects of HPV vaccines include soreness, swelling or redness at the injection site.

 

What is the dosage for Gardasil Vaccine (HPV)?

Gardasil 0.5 ml is injected intramuscularly as three separate doses. The first dose is administered at the patient's convenience, the second dose two months after the first dose, and the third dose six months after the first dose.

 

Why is HPV vaccination recommended?

1. One out of 4 women who die of cervical cancer is from India.
2. Every seven minutes one woman dies of cervical cancer in India.
3. Cervical cancer kills roughly 67,477 Indian women annually.
4. Human Papilloma Virus (HPV) has been detected in 99.7% of all cases of Cervical Cancer worldwide.
5. This is the highest level of the associated pathogen known to be a major cause for a human form of Cancer.
6. HPV types 16 and 18 are responsible for 82% of cervical cancers in India.

Does it apply only to girls or do boys have to take it as well?

There is increasing evidence that boys are infected with HPV as well. MSD has launched the gender neutral Gardasil 9 in India. The rationale behind this is that the vaccine would prevent Genital warts, oral cancers, penile cancers, anal cancers and precancerous lesions, especially in homosexual identities. 
(https://www.livemint.com/companies/news/msd-india-launches-9-valent-human-papillomavirus-vaccine-gardasil9-11632914111895.html)

India has also launched its own vaccine under the name Cervivac made by the Serum Institute which brings down the cost considerably 

Do get in touch with me for any further information you may need. I'll be happy to help!

Meanwhile, here are some more newspaper articles for the movement currently on in India.

https://www.hindustantimes.com/india/is-hpv-vaccine-safe-for-my-daughter-yes/story-4gBa5z5rDtxREhNJ6lzzQP.html

https://www.news18.com/news/buzz/dear-indian-women-did-you-know-that-there-is-a-vaccine-for-cervical-cancer-3390860.html

IAP (Indian Association of Pediatricians) - https://acvip.org/parents/columns/cervical-cancer.php